SCHEMBL3983134

SCHEMBL3983134

O=C(O)C(Cc1ccc(O)cc1)NC(C(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.59
NAALAD2 Q9Y3Q0 1/20 0.55
SLC7A5 Q01650 1/20 0.53
MME P08473 7/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
ACE P12821 7/20 0.50
CPA1 P15085 1/20 0.50
ACE2 Q9BYF1 1/20 0.50
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3983123 1.00 FOLH1 (0.59) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL9847993 0.84 FOLH1 (0.54) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL9847998 0.84 FOLH1 (0.54) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL5738141 0.84 FOLH1 (0.61) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL12869808 0.84 FOLH1 (0.61) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL5869469 0.83 FOLH1 (0.74) FOLH1NAALAD2MMEACECPA1
SCHEMBL5869992 0.83 FOLH1 (0.74) FOLH1NAALAD2MMEACECPA1
SCHEMBL22612664 0.83 FOLH1 (0.60) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL29444963 0.83 FOLH1 (0.60) FOLH1NAALAD2SLC7A5MMEMEN1
SCHEMBL156975 0.81 FOLH1 (0.58) FOLH1NAALAD2SLC7A5MMEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115997121-A Composition for endometriosis assessment with improved specificity 艾思彼拉妇女保健公司 2023-04-21 CN disclosed
CN-105823877-B Biomarkers for ovarian cancer: CTAP 3-related protein 约翰·霍普金斯大学 2022-02-25 CN disclosed
US-20170089906-A1 BIOMARKERS FOR OVARIAN CANCER VERMILLION, INC. (US) 2017-03-30 US disclosed
CN-105823877-A Biomarker for ovarian cancer CTAP3-related proteins 约翰·霍普金斯大学 2016-08-03 CN disclosed
CN-101243319-B Biomarkers for ovarian cancer: CTAP 3-related protein THE JOHNS HOPKINS UNIVERSITY (US) 2016-01-06 CN disclosed
US-20140038899-A1 BIOMARKERS FOR OVARIAN CANCER THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2014-02-06 US disclosed
EP-1910821-B1 BIOMARKERS FOR OVARIAN CANCER CIPHERGEN BIOSYSTEMS INC (US) 2013-02-20 EP disclosed
EP-1910821-A4 BIOMARKERS FOR OVARIAN CANCER CIPHERGEN BIOSYSTEMS INC (US) 2009-05-13 EP disclosed
US-20080274481-A1 Methods for diagnosing ovarian cancer VERMILLION, INC. (US) 2008-11-06 US disclosed
WO-2008121340-A1 METHODS FOR DIAGNOSING OVARIAN CANCER VERMILLION, INC. (US) 2008-10-09 WO disclosed
EP-1910821-A2 BIOMARKERS FOR OVARIAN CANCER Ciphergen Biosystems, Inc. (US) 2008-04-16 EP disclosed
WO-2007002535-A2 BIOMARKERS FOR OVARIAN CANCER CIPHERGEN BIOSYSTEMS, INC. (US) 2007-01-04 WO disclosed