⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505552 | 0.84 | — | — | |
| SCHEMBL10897425 | 0.76 | — | — | |
| SCHEMBL8283501 | 0.74 | EPHX1 (0.31) | — | |
| SCHEMBL9004334 | 0.72 | CHRM2 (0.34) | — | |
| SCHEMBL17264874 | 0.71 | CHRM2 (0.37) | — | |
| SCHEMBL9868926 | 0.71 | CHRM2 (0.37) | — | |
| SCHEMBL17264875 | 0.71 | CHRM2 (0.37) | — | |
| SCHEMBL8472385 | 0.69 | — | — | |
| SCHEMBL8281878 | 0.69 | CHRM2 (0.35) | — | |
| SCHEMBL8281881 | 0.69 | CHRM2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374011-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | UNICHEM LABORATORIES LTD. (IN) | 2023-11-23 | — | — | US | disclosed |
| WO-2023194840-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AND THEIR USE IN COVID-19 | UNICHEM LABORATORIES LIMITED (IN) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023194842-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AND THEIR USE IN RHEUMATOID ARTHRITIS | UNICHEM LABORATORIES LIMITED (IN) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023194841-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AND THEIR USE IN ULCERATIVE COLITIS | UNICHEM LABORATORIES LIMITED (IN) | 2023-10-12 | — | — | WO | disclosed |
| EP-4225442-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Unichem Laboratories Ltd (IN) | 2023-08-16 | — | — | EP | disclosed |
| US-20090131720-A1 | PROCESS FOR THE SYNTHESIS OF HYDROXYL ARYLAMINES | XEROX CORPORATION (US) | 2009-05-21 | — | — | US | disclosed |
| US-7482492-B2 | Cost effective method for synthesis of triarylamine compounds | XEROX CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |
| US-20080255389-A1 | COST EFFECTIVE METHOD FOR SYNTHESIS OF TRIARYLAMINE COMPOUNDS | XEROX CORPORATION (US) | 2008-10-16 | — | — | US | disclosed |
| US-7312330-B2 | Bicycloheteroarylamine compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| WO-2006118598-A1 | BICYCLOHETEROARYLAMINE COMPOUNDS AS ION CHANNEL LIGANDS AND USES THEREOF | RENOVIS, INC. (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20050277643-A1 | Bicycloheteroarylamine compounds as ion channel ligands and uses thereof | EVOTEC AG (DE) | 2005-12-15 | — | — | US | disclosed |
| US-5484895-A | OF A VASCULAR PLANT, A THERMOPLASTIC AND A GRAFTED LAYER | MEISTER, JOHN J. | 1996-01-16 | — | — | US | disclosed |