⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39850 | 1.00 | — | — | |
| SCHEMBL39918 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30998361 | 0.98 | EPHX1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL22655490 | 0.98 | EPHX1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL1898155 | 0.98 | EPHX1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL3948434 | 0.98 | EPHX1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL28300547 | 0.98 | EPHX1 (0.48) | — | |
| SCHEMBL1321300 | 0.88 | MAPK1 (0.50) | — | |
| SCHEMBL1006531 | 0.88 | MAPK1 (0.50) | — | |
| SCHEMBL11949315 | 0.88 | MAPK1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 961 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030878-B2 | Substituted indole ether compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-09 | — | — | US | claimed |
| CN-112135820-B | Novel process for preparing diaminopyrimidine derivatives or acid addition salts thereof | 柳韩洋行 | 2024-01-02 | — | — | CN | claimed |
| US-11434224-B2 | Processes for preparing a diaminopyrimidine derivative or acid addition salt thereof | YUHAN CORPORATION (KR) | 2022-09-06 | — | — | US | claimed |
| US-20210206746-A1 | NOVEL PROCESSES FOR PREPARING A DIAMINOPYRIMIDINE DERIVATIVE OR ACID ADDITION SALT THEREOF | YUHAN CORPORATION (KR) | 2021-07-08 | — | — | US | claimed |
| EP-3797104-A1 | NOVEL PROCESSES FOR PREPARING A DIAMINOPYRIMIDINE DERIVATIVE OR ACID ADDITION SALT THEREOF | Yuhan Corporation (KR) | 2021-03-31 | — | — | EP | claimed |
| CN-112135820-A | Novel process for preparing diaminopyrimidine derivatives or their acid addition salts | 柳韩洋行 | 2020-12-25 | — | — | CN | claimed |
| EP-3286192-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AND METHOD OF USE | AbbVie Deutschland GmbH & Co KG (DE) | 2018-02-28 | — | — | EP | claimed |
| WO-2016169995-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AND METHOD OF USE | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-10-27 | — | — | WO | claimed |
| WO-2013130660-A1 | AMIDES AS PIM INHIBITORS | AMGEN INC. (US) | 2013-09-06 | — | — | WO | claimed |
| US-20120301426-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-11-29 | — | — | US | claimed |
| CN-1425365-A | 2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre | OREAL (FR) | 2003-06-25 | — | — | CN | claimed |
| EP-1312606-A1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | L'OREAL (FR) | 2003-05-21 | — | — | EP | claimed |
| EP-1218384-A4 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2002-11-20 | — | — | EP | claimed |
| EP-1218384-A1 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023392-A1 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-05 | — | — | WO | claimed |
| EP-0331960-B1 | Process for the preparation of enantiomerically homogeneous aminopyrrolidinyl naphthyridine and quinolone carboxylic acids | ABBOTT LAB (US) | 1994-05-18 | — | — | EP | claimed |
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | claimed |
| US-4956475-A | REDUCTIVE ACETYLATION OF THE 3-AZIDO DERIVATIVE USING THIOACETIC ACID TO OBTAIN THE CORRESPONDING ACETAMIDE | ABBOTT LABORATORIES (US) | 1990-09-11 | — | — | US | claimed |
| EP-0331960-A2 | Process for the preparation of enantiomerically homogeneous aminopyrrolidinyl naphthyridine and quinolone carboxylic acids | ABBOTT LABORATORIES (US) | 1989-09-13 | — | — | EP | claimed |
| US-4859776-A | (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation | ABBOTT LABORATORIES (US) | 1989-08-22 | — | — | US | claimed |