⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17789626 | 0.80 | — | — | |
| SCHEMBL9451842 | 0.78 | — | — | |
| SCHEMBL13079166 | 0.77 | — | — | |
| SCHEMBL14980243 | 0.77 | — | — | |
| SCHEMBL16326349 | 0.77 | — | — | |
| SCHEMBL3368132 | 0.77 | — | — | |
| SCHEMBL11370139 | 0.77 | — | — | |
| SCHEMBL16021722 | 0.76 | — | — | |
| SCHEMBL9880281 | 0.75 | — | — | |
| SCHEMBL460532 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776972-B2 | Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof | EPIZYME INC. (US) | 2017-10-03 | — | — | US | disclosed |
| EP-2875021-B1 | BETA AMINO ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | UNIV SAINT LOUIS (US) | 2017-08-23 | — | — | EP | disclosed |
| US-9669027-B2 | Hepatitis C virus inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2017-06-06 | — | — | US | disclosed |
| US-20170073305-A1 | FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE | CATABASIS PHARMACEUTICALS, INC. | 2017-03-16 | — | — | US | disclosed |
| US-20160264581-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | Janssen Pharmaceuticals, Inc. | 2016-09-15 | — | — | US | disclosed |
| US-20160228438-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | ALIOS BIOPHARMA, INC. | 2016-08-11 | — | — | US | disclosed |
| US-20160152626-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
| US-20160137609-A1 | PYRAZOLE DERIVATIVES AS ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160122358-A1 | NOVEL SUBSTITUTED PYRAZOLO-PIPERAZINES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-05-05 | — | — | US | disclosed |
| US-9328119-B2 | AZA-pyridone compounds and uses thereof | ALIOS BIOPHARMA, INC. (US) | 2016-05-03 | — | — | US | disclosed |
| US-20110065739-A1 | NOVEL ISOXAZOLE DRIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20100240653-A1 | BIPHENYL SULFONYL AND PHENYL-HETEROARYL SULFONYL MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2010-09-23 | — | — | US | disclosed |
| US-20100158927-A1 | ANTIBODIES, METHODS AND KITS FOR DIAGNOSING AND TREATING MELANOMA | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-06-24 | — | — | US | disclosed |
| US-20090325930-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATOR | RADIUS HEALTH, INC. | 2009-12-31 | — | — | US | disclosed |
| EP-2061738-B1 | PROCESS FOR THE PRODUCTION OF HYDROCARBONS | BP OIL INT (GB) | 2009-12-30 | — | — | EP | disclosed |
| US-20090203723-A1 | 6,7-unsaturated-7-carbamoyl substituted morphinan derivative | SHIONOGI & CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090203949-A1 | Process for the production of hydrocarbons | BP OIL INTERNATIONAL LIMITED | 2009-08-13 | — | — | US | disclosed |
| EP-2061738-A1 | PROCESS FOR THE PRODUCTION OF HYDROCARBONS | BP Oil International Limited (GB) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008032015-A1 | PROCESS FOR THE PRODUCTION OF HYDROCARBONS | BP OIL INTERNATIONAL LIMITED (GB) | 2008-03-20 | — | — | WO | disclosed |
| EP-1900714-A1 | Process for the production of hydrocarbons | BP OIL INTERNATIONAL LIMITED (GB) | 2008-03-19 | — | — | EP | disclosed |