Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4248742 | 0.95 | PARP1 (0.66) | PARP1KCNH2 | |
| SCHEMBL20544239 | 0.86 | PARP1 (0.65) | PARP1 | |
| SCHEMBL20544682 | 0.85 | PARP1 (0.73) | PARP1 | |
| SCHEMBL20544688 | 0.84 | PARP1 (0.68) | PARP1 | |
| SCHEMBL20544503 | 0.84 | PARP1 (1.00) | PARP1 | |
| SCHEMBL3920570 | 0.83 | PARP1 (0.68) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL3916008 | 0.81 | PARP1 (0.59) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL3980202 | 0.81 | PARP1 (0.67) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL3085468 | 0.80 | PARP1 (0.62) | PARP1 | |
| SCHEMBL20544245 | 0.80 | PARP1 (1.00) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029551-B1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | MSD ITALIA SRL (IT) | 2018-10-31 | — | — | EP | claimed |
| EP-2029551-A2 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007138351-A2 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-12-06 | — | — | WO | disclosed |