⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877447 | 1.00 | — | — | |
| SCHEMBL1877444 | 1.00 | — | — | |
| SCHEMBL3622263 | 0.79 | HCAR2 (0.53) | — | |
| SCHEMBL2468754 | 0.77 | — | — | |
| SCHEMBL7656034 | 0.74 | — | — | |
| SCHEMBL7656039 | 0.74 | — | — | |
| SCHEMBL7664562 | 0.74 | — | — | |
| SCHEMBL7168184 | 0.74 | — | — | |
| SCHEMBL7664566 | 0.74 | — | — | |
| SCHEMBL823187 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315421-B1 | ORGANOPHOSPHOROUS COMPOSITIONS | BASF CORP (US) | 2004-06-02 | — | — | EP | claimed |
| EP-0439096-B1 | Improvements in or relating to beta lactam production | BIOCHEMIE GMBH (AT) | 2003-12-17 | — | — | EP | claimed |
| US-5604225-A | DIETETICS; OBESITY | DR. KARL THOMAE GMBH (DE) | 1997-02-18 | — | — | US | claimed |
| US-5457205-A | Substituted thiazoles useful for treatment of diabetes | DR. KARL THOMAE GMBH (DE) | 1995-10-10 | — | — | US | claimed |
| EP-0292806-B1 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1994-11-02 | — | — | EP | claimed |
| US-5219852-A | Hypoglycemic agents, treatment of diabetes and obesity | DR. KARL THOMAE GMBH (DE) | 1993-06-15 | — | — | US | claimed |
| EP-0239815-B1 | SUBSTITUTED THIAZOLES AND OXAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1991-07-24 | — | — | EP | claimed |
| US-5026702-A | Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins | DR. KARL THOMAE, GMBH (DE) | 1991-06-25 | — | — | US | claimed |
| EP-0197294-B1 | BETA-LACTAM ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1991-04-03 | — | — | EP | claimed |
| EP-0292806-A2 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1988-11-30 | — | — | EP | claimed |
| US-4582829-A | Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds | PFIZER INC. (US) | 1986-04-15 | — | — | US | claimed |
| US-4540687-A | Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds | PFIZER INC. (US) | 1985-09-10 | — | — | US | claimed |
| EP-0121383-A1 | Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides | PFIZER INC. (US) | 1984-10-10 | — | — | EP | claimed |
| EP-0102226-A1 | Bis-esters of 4,5-di(hydroxymethyl)-2-oxo-1,3-dioxole as antibacterial agents | PFIZER INC. (US) | 1984-03-07 | — | — | EP | claimed |
| US-4434173-A | Bis-esters of 4,5-di(hydroxymethyl)-2-oxo-1,3-dioxole as antibacterial agents | PFIZER INC. (US) | 1984-02-28 | — | — | US | claimed |
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | claimed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-4245088-A | Novel 3-acyloxymethyl-cephem compounds useful as intermediates for preparing cephalosporin antibiotics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | claimed |
| US-4166178-A | 3-ACYLOXYMETHYL-CEPHEM COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-08-28 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |