Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.35 |
| ▸ | MC3R | P41968 | 3/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | FCER2 | P06734 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | MC1R | Q01726 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13795596 | 1.00 | MC4R (0.35) | MC4RMC3RRENOPRD1FCER2 | |
| SCHEMBL13796832 | 0.94 | MC4R (0.34) | MC4RMC3RREN | |
| SCHEMBL13796806 | 0.91 | MC4R (0.34) | MC4RMC3R | |
| SCHEMBL13796434 | 0.90 | MC4R (0.36) | MC4RMC3RRENFCER2 | |
| SCHEMBL13796438 | 0.90 | MC4R (0.37) | MC4RMC3RRENOPRD1 | |
| SCHEMBL13796432 | 0.90 | MC4R (0.33) | MC4RMC3R | |
| SCHEMBL13795947 | 0.89 | BACE1 (0.33) | MC4RMC3R | |
| SCHEMBL13796436 | 0.87 | BACE1 (0.34) | MC4RMC3RREN | |
| SCHEMBL3989661 | 0.87 | BACE1 (0.34) | MC4RMC3RREN | |
| SCHEMBL13796741 | 0.87 | MC4R (0.31) | MC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | claimed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | claimed |
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |