Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.45 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.45 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45585 | 0.91 | MTOR (0.46) | MTORRPTORMLST8 | |
| SCHEMBL45650 | 0.91 | MTOR (0.45) | MTORRPTORMLST8 | |
| SCHEMBL45689 | 0.90 | MTOR (0.47) | MTORRPTORMLST8 | |
| SCHEMBL31381 | 0.90 | MTOR (0.56) | MTORRPTORMLST8 | |
| SCHEMBL15026244 | 0.89 | MTOR (0.47) | MTORRPTORMLST8 | |
| SCHEMBL15026243 | 0.88 | MTOR (0.48) | MTORRPTORMLST8 | |
| SCHEMBL45734 | 0.87 | MTOR (0.47) | MTORRPTORMLST8 | |
| SCHEMBL15026248 | 0.87 | MTOR (0.47) | MTORRPTORMLST8 | |
| SCHEMBL45630 | 0.86 | MTOR (0.46) | MTORRPTORMLST8 | |
| SCHEMBL45694 | 0.85 | MTOR (0.40) | MTORRPTORMLST8ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027234-A1 | FUSED TRICYCLIC INHIBITORS OF MAMMALIAN TARGET OF RAPAMYCIN | SCHERING CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |