Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | APOBEC3B | Q9UH17 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852353 | 0.76 | KDM4C (0.55) | KDM4CKMT2AL3MBTL1KDM4DMEN1 | |
| SCHEMBL30804202 | 0.76 | KDM4C (0.55) | KDM4CKMT2AL3MBTL1KDM4DMEN1 | |
| SCHEMBL4004484 | 0.76 | KMT2A (0.45) | KMT2AL3MBTL1MEN1ALDH1A1EPHX2 | |
| SCHEMBL4768904 | 0.74 | KDM4C (0.53) | KDM4CKMT2AL3MBTL1KDM4DMEN1 | |
| SCHEMBL11590329 | 0.71 | TDP1 (0.42) | KDM4CKMT2AL3MBTL1KDM4DMEN1 | |
| SCHEMBL11819131 | 0.67 | KDM4C (0.46) | KDM4CKMT2AL3MBTL1KDM4DMEN1 | |
| SCHEMBL437592 | 0.67 | TP53 (0.50) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL27711603 | 0.64 | KDM4C (0.42) | KDM4CKMT2AL3MBTL1KDM4DMEN1 | |
| SCHEMBL11704503 | 0.63 | CA1 (0.59) | KMT2AL3MBTL1MEN1KDM4EMAPT | |
| SCHEMBL28854487 | 0.62 | KMT2A (0.57) | KDM4CKMT2AKDM4DMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675552-A4 | PREPERATION OF 1,6-DISUBSTITUTED AZABENZIMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2009-06-03 | — | — | EP | disclosed |
| EP-1675552-A2 | PREPERATION OF 1,6-DISUBSTITUTED AZABENZIMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005037197-A2 | PREPERATION OF 1,6-DISUBSTITUTED AZABENZIMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-04-28 | — | — | WO | disclosed |