Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1328516 | 0.87 | TDP1 (0.46) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL2152898 | 0.80 | TDP1 (0.51) | IDO1TDP1CA12CA1CA2 | |
| SCHEMBL20500779 | 0.79 | TDP1 (0.59) | IDO1TDP1CA12CA1CA2 | |
| SCHEMBL19928735 | 0.79 | TDP1 (0.69) | IDO1TDP1CA12CA1CA2 | |
| SCHEMBL31255326 | 0.78 | TDP1 (0.46) | IDO1TDP1CA12CA1CA2 | |
| SCHEMBL1329660 | 0.77 | TDP1 (0.51) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL27148633 | 0.77 | TDP1 (0.51) | IDO1TDP1CA12CA1CA2 | |
| SCHEMBL30206955 | 0.77 | TDP1 (0.55) | IDO1TDP1CA12CA1CA2 | |
| SCHEMBL19746137 | 0.76 | TDP1 (0.70) | IDO1TDP1CA12CA1CA2 | |
| SCHEMBL28134802 | 0.76 | TDP1 (0.50) | IDO1TDP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067233-A1 | BETA CARBOLINES AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | WO | disclosed |