Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998758 | 0.95 | TACR1 (0.35) | TACR1S1PR1SLC6A4 | |
| SCHEMBL4000453 | 0.93 | CETP (0.33) | S1PR1CETP | |
| SCHEMBL4001632 | 0.93 | — | — | |
| SCHEMBL4005245 | 0.90 | — | — | |
| SCHEMBL4000728 | 0.89 | TACR1 (0.32) | TACR1S1PR1 | |
| SCHEMBL4004874 | 0.89 | — | — | |
| SCHEMBL4001348 | 0.88 | CETP (0.33) | TACR1CETPALDH1A1SLC6A4 | |
| SCHEMBL3999424 | 0.87 | TACR1 (0.34) | TACR1 | |
| SCHEMBL3997289 | 0.87 | SLC6A2 (0.37) | TACR1CETPSLC6A4 | |
| SCHEMBL3998806 | 0.85 | TACR1 (0.34) | TACR1CETPSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076404-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2009-06-18 | — | — | WO | claimed |
| WO-2009076404-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2009-06-18 | — | — | WO | disclosed |