Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3994210 | 0.94 | CNR2 (0.47) | LTB4R2LTB4RALOX5CNR2PLG | |
| SCHEMBL4631074 | 0.91 | CNR2 (0.59) | LTB4R2LTB4RALOX5CNR2PLG | |
| SCHEMBL4002651 | 0.91 | LTB4R2 (0.53) | LTB4R2LTB4RALOX5CNR2 | |
| SCHEMBL4001522 | 0.90 | CYP1A2 (0.48) | ALOX5CNR2PLGPRSS1PRSS2 | |
| SCHEMBL3997809 | 0.86 | CNR2 (0.48) | LTB4R2LTB4RALOX5CNR2 | |
| SCHEMBL4630671 | 0.86 | LTB4R2 (0.55) | LTB4R2ALOX5CNR2PLGPRSS1 | |
| SCHEMBL3996532 | 0.86 | CNR2 (0.48) | LTB4R2LTB4RALOX5CNR2CA12 | |
| SCHEMBL4003245 | 0.83 | CYP1A2 (0.49) | LTB4R2LTB4RALOX5CNR2 | |
| SCHEMBL4630064 | 0.82 | CNR2 (0.62) | LTB4R2ALOX5CNR2 | |
| SCHEMBL4004959 | 0.82 | CNR2 (0.52) | LTB4R2LTB4RCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |
| US-20050267149-A1 | Benzoic acid derivatives as modulators of ppar alpha and gamma | ASTRAZENECA AB (SE) | 2005-12-01 | — | — | US | disclosed |
| EP-1517680-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | Astrazeneca AB (SE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000295-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267149-A1 | Benzoic acid derivatives as modulators of ppar alpha and gamma | PPARG, NR4A1, NR0B1 | LTB4R2 1032/4885LTB4R 1131/4885ALOX5 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.