Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.49 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3999730 | 0.85 | SSTR5 (0.53) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3999738 | 0.84 | SSTR5 (0.53) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3999701 | 0.79 | SSTR5 (0.53) | SSTR5 | |
| SCHEMBL1876982 | 0.78 | SSTR5 (0.57) | SSTR5KCNH2SSTR3 | |
| SCHEMBL1878211 | 0.75 | SSTR5 (0.53) | SSTR5 | |
| SCHEMBL3998958 | 0.75 | SSTR5 (0.53) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3995690 | 0.74 | SSTR5 (0.43) | SSTR5 | |
| SCHEMBL4000990 | 0.72 | SSTR5 (0.52) | SSTR5KCNH2SSTR3 | |
| SCHEMBL4233908 | 0.71 | SSTR5 (0.44) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3873987 | 0.71 | SSTR5 (0.68) | SSTR5KCNH2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066658-A1 | PYRIDINE- AND QUINOLINE-PYRIMIDINE-DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008031735-A1 | PYRIDINE- AND QUINOLINE-PYRIMIDINE-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-03-20 | — | — | WO | disclosed |