Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 17/20 | 0.64 |
| ▸ | TACR1 | P25103 | 16/20 | 0.64 |
| ▸ | TAC3 | Q9UHF0 | 6/20 | 0.64 |
| ▸ | TACR3 | P29371 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998525 | 1.00 | TACR2 (0.64) | TACR2TACR1TAC3TACR3POLB | |
| SCHEMBL4153213 | 0.92 | TACR2 (0.68) | TACR2TACR1TAC3TACR3POLB | |
| SCHEMBL4155827 | 0.85 | TACR2 (0.74) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4159872 | 0.83 | TACR2 (0.85) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4149393 | 0.83 | TACR2 (0.68) | TACR2TACR1TAC3TACR3SMN1; SMN2 | |
| SCHEMBL4146339 | 0.81 | TACR2 (0.76) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4146335 | 0.81 | TACR2 (0.76) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4157150 | 0.81 | TACR2 (0.81) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4150770 | 0.81 | TACR1 (0.69) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4000380 | 0.80 | TACR2 (0.82) | TACR2TACR1TAC3TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072643-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-11 | — | — | WO | disclosed |