Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39714 | 0.91 | SLC34A2 (0.51) | SLC34A2BRAFKDM4ERAF1MEN1 | |
| SCHEMBL39840 | 0.91 | SLC34A2 (0.45) | SLC34A2BRAFKDM4ERAF1MEN1 | |
| SCHEMBL6000691 | 0.90 | SLC34A2 (0.49) | SLC34A2BRAFKDM4ERAF1MEN1 | |
| SCHEMBL39860 | 0.90 | SLC34A2 (0.53) | SLC34A2BRAFKDM4ERAB9ARAF1 | |
| SCHEMBL16355250 | 0.90 | SLC34A2 (0.51) | SLC34A2BRAFKDM4ERAF1HRH4 | |
| SCHEMBL40075 | 0.90 | SLC34A2 (0.52) | SLC34A2BRAFKDM4ERAF1HRH4 | |
| SCHEMBL39843 | 0.90 | SLC34A2 (0.51) | SLC34A2BRAFKDM4ERAF1MEN1 | |
| SCHEMBL15432502 | 0.90 | SLC34A2 (0.52) | SLC34A2BRAFKDM4ERAF1MEN1 | |
| SCHEMBL46515 | 0.90 | SLC34A2 (0.51) | SLC34A2BRAFKDM4ERAF1MEN1 | |
| SCHEMBL46729 | 0.90 | SLC34A2 (0.46) | SLC34A2BRAFKDM4ERAF1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |