Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8983576 | 0.98 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL3994479 | 0.94 | CYP3A4 (0.49) | NPC1RAB9ASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL14382312 | 0.93 | CYP3A4 (0.51) | NPC1RAB9ASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL1568984 | 0.90 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL2006083 | 0.82 | MAPT (0.52) | NPC1RAB9ASMN1; SMN2HSD17B10POLB | |
| SCHEMBL7876171 | 0.79 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL20381746 | 0.78 | MAPT (0.44) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL8353939 | 0.78 | KDM4E (0.42) | RAB9AMEN1KMT2APOLBMAPK1 | |
| SCHEMBL16466281 | 0.78 | APP (0.40) | MEN1KMT2APOLBMAPT | |
| SCHEMBL3104534 | 0.77 | KDM4E (0.44) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591624-B1 | Process for the preparation of pure 2,5-dichloropyridine and the isolation of 2,3-dichloropyridine which is formed as a by-product | RUETGERSWERKE AG (DE) | 1996-06-05 | — | — | EP | claimed |
| US-5380862-A | Preparation of isomer-free 2,5-dichloro-pyridine | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | claimed |
| EP-0591624-A1 | Process for the preparation of pure 2,5-dichloropyridine and the isolation of 2,3-dichloropyridine which is formed as a by-product | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1994-04-13 | — | — | EP | claimed |
| CN-118307468-A | Method for preparing 2, 3-dichloropyridine | 利尔化学股份有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-117358270-A | Catalyst for synthesizing 2,3-dichloropyridine and preparation method and application thereof | 利尔化学股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-113292486-A | One-pot synthesis method of 2, 3-dichloropyridine | 安徽星宇化工有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-109721529-B | Simple preparation method of 2, 5-dichloropyridine | 新发药业有限公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-109721529-A | A kind of simple and convenient process for preparing of 2,5- dichloropyridine | 新发药业有限公司 | 2019-05-07 | — | — | CN | disclosed |
| WO-2015129813-A1 | DEUTERATION METHOD AND DEUTERATION CATALYST | 国立大学法人 長崎大学 | 2015-09-03 | — | — | WO | disclosed |
| EP-2080758-A2 | Halogen substituted delta-1-pyrrolines | Bayer CropScience AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-2080758-A2 | Halogen substituted delta-1-pyrrolines | Bayer CropScience AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2009068194-A2 | HALOGEN-SUBSTITUTED Δ1 PYRROLINES | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | WO | disclosed |
| WO-2009068194-A2 | HALOGEN-SUBSTITUTED Δ1 PYRROLINES | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | WO | disclosed |
| EP-0591624-B1 | Process for the preparation of pure 2,5-dichloropyridine and the isolation of 2,3-dichloropyridine which is formed as a by-product | RUETGERSWERKE AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| US-5380862-A | Preparation of isomer-free 2,5-dichloro-pyridine | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| EP-0591624-A1 | Process for the preparation of pure 2,5-dichloropyridine and the isolation of 2,3-dichloropyridine which is formed as a by-product | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1994-04-13 | — | — | EP | disclosed |