Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956125 | 0.86 | HTR2C (0.74) | HTR2CHTR2AHTR2BHTR6GRM7 | |
| SCHEMBL6386133 | 0.82 | HTR2C (0.69) | HTR2CHTR2AHTR2BHTR6GRM7 | |
| SCHEMBL30603834 | 0.80 | HTR2C (0.67) | HTR2CHTR2AHTR2BHTR6MEN1 | |
| SCHEMBL1128139 | 0.80 | HTR2C (0.67) | HTR2CHTR2AHTR2BHTR6MEN1 | |
| SCHEMBL5584737 | 0.77 | HTR2C (1.00) | HTR2CHTR6 | |
| SCHEMBL5584733 | 0.77 | HTR2C (0.62) | HTR2CHTR2AHTR2BHTR6GRM7 | |
| Hydrochloric Acid SCHEMBL31109384 | 0.76 | HTR2C (1.00) | HTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL21855666 | 0.76 | HTR2C (1.00) | HTR2CHTR6 | |
| SCHEMBL18647026 | 0.74 | HTR2C (0.59) | HTR2CHTR2AHTR2BHTR6GRM7 | |
| SCHEMBL21939477 | 0.74 | HTR2C (0.59) | HTR2CHTR2AHTR2BHTR6GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079551-A1 | HETEROGENEOUS PROMOTION OF OXIRANE HYDROFORMYLATION | SHELL OIL COMPANY (US) | 2009-06-25 | — | — | WO | disclosed |