⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061965 | 0.92 | — | — | |
| SCHEMBL901657 | 0.92 | — | — | |
| SCHEMBL901658 | 0.92 | — | — | |
| SCHEMBL21505052 | 0.73 | — | — | |
| SCHEMBL238816 | 0.71 | — | — | |
| SCHEMBL21505049 | 0.71 | — | — | |
| SCHEMBL14996909 | 0.71 | — | — | |
| SCHEMBL3108689 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL16227077 | 0.69 | — | — | |
| SCHEMBL13436389 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253744-A1 | Acylated piperidine derivatives as melanocortin-4 receptor modulators | MERCK SHARP & DOHME CORP. | 2009-10-08 | — | — | US | disclosed |
| EP-2068867-A2 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008039418-A2 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2008-04-03 | — | — | WO | disclosed |
| CN-1128149-C | 6,9-Disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | CN | disclosed |
| CN-1291983-A | 6,9-Disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | AVENTIS PHARMA INC (US) | 2001-04-18 | — | — | CN | disclosed |
| US-5750553-A | ANTIANDROGENIC AGENTS | ROUSSEL UCLAF (FR) | 1998-05-12 | — | — | US | disclosed |