Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 19/20 | 0.90 |
| ▸ | TACR1 | P25103 | 18/20 | 0.90 |
| ▸ | TAC3 | Q9UHF0 | 6/20 | 0.90 |
| ▸ | TACR3 | P29371 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002162 | 1.00 | TACR2 (0.90) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4154149 | 0.95 | TACR2 (1.00) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4154146 | 0.95 | TACR2 (1.00) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4162051 | 0.93 | TACR2 (0.89) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4141048 | 0.92 | TACR2 (1.00) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4149699 | 0.92 | TACR2 (0.90) | TACR2TACR1TAC3TACR3 | |
| Water SCHEMBL4140787 | 0.91 | TACR2 (0.98) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4150753 | 0.89 | TACR2 (0.77) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4153242 | 0.89 | TACR2 (0.77) | TACR2TACR1TAC3TACR3 | |
| SCHEMBL4144833 | 0.88 | TACR2 (0.90) | TACR2TACR1TAC3TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072643-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-11 | — | — | WO | disclosed |