SCHEMBL4002183

SCHEMBL4002183

CC(C)(C)c1nc2cc(CCl)ccc2n1CC1CCOCC1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.66
CNR1 P21554 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3997990 0.89 CNR2 (0.67) CNR2CNR1
SCHEMBL3997694 0.86 CNR2 (0.62) CNR2CNR1
SCHEMBL13450109 0.85 CNR2 (0.69) CNR2CNR1
SCHEMBL3997866 0.84 CNR2 (0.68) CNR2CNR1
SCHEMBL4005446 0.84 CNR2 (0.60) CNR2CNR1
SCHEMBL4000754 0.84 CNR2 (0.68) CNR2CNR1
SCHEMBL1609531 0.84 CNR2 (0.68) CNR2CNR1
SCHEMBL13605698 0.84 CNR2 (0.68) CNR2CNR1
Hydrochloric Acid SCHEMBL1609279 0.83 CNR2 (0.67) CNR2CNR1
SCHEMBL3999621 0.82 CNR2 (0.66) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598393-B2 Sulfonyl benzimidazole derivatives PFIZER INC. (US) 2009-10-06 US disclosed
EP-1809607-B1 SULFONYL BENZIMIDAZOLE DERIVATIVES PFIZER (US) 2008-12-17 EP disclosed
US-20060094750-A1 Sulfonyl benzimidazole derivatives KON-I KANA 2006-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094750-A1 Sulfonyl benzimidazole derivatives TRPV1, CNR2, CNR1 CNR2 2/4885CNR1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.