Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25229608 | 0.76 | NPSR1 (0.31) | — | |
| SCHEMBL2824808 | 0.75 | CYP4F2 (0.41) | CYP4F2CYP4A11 | |
| SCHEMBL28419664 | 0.75 | CYP4F2 (0.41) | CYP4F2CYP4A11 | |
| SCHEMBL18208201 | 0.72 | CYP4F2 (0.45) | CYP4F2CYP4A11 | |
| SCHEMBL16142012 | 0.69 | CYP4F2 (0.45) | CYP4F2CYP4A11 | |
| SCHEMBL356203 | 0.69 | CYP4F2 (0.49) | CYP4F2CYP4A11 | |
| SCHEMBL16142018 | 0.68 | CYP4F2 (0.47) | CYP4F2CYP4A11 | |
| SCHEMBL9886223 | 0.68 | CYP4F2 (0.51) | CYP4F2CYP4A11 | |
| SCHEMBL4763096 | 0.66 | CYP4F2 (0.41) | CYP4F2CYP4A11 | |
| SCHEMBL6268373 | 0.65 | CYP4F2 (0.70) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009059-A1 | SPIRO COMPOUNDS AS ANTAGONISTS OF TGF-BETA | BIOGEN IDEC MA INC. (US) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009009059-A1 | SPIRO COMPOUNDS AS ANTAGONISTS OF TGF-BETA | BIOGEN IDEC MA INC. (US) | 2009-01-15 | — | — | WO | disclosed |