SCHEMBL4004245

SCHEMBL4004245

C/C=C\CC[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96833 1.00
SCHEMBL96834 1.00
SCHEMBL7289512 0.94 PPARG (0.31)
SCHEMBL7289510 0.94 PPARG (0.31)
SCHEMBL7463356 0.82
SCHEMBL7463358 0.82
SCHEMBL15400347 0.80
SCHEMBL98124 0.80
SCHEMBL98123 0.80
SCHEMBL1141690 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5380462-A Cyclohexyl alkenoate compounds HOFFMANN-LA ROCHE INC. (US) 1995-01-10 US claimed
CN-116018136-A Hypoxia-inducible factor prolyl hydroxylase inhibitors for the treatment of aging-related disorders 百爱及生物医药公司 2023-04-25 CN disclosed
US-20210353612-A1 HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE INHIBITORS FOR TREATING AGING-RELATED CONDITIONS BioAge Labs, Inc. 2021-11-18 US disclosed
EP-2881384-B1 PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND TAISHO PHARMACEUTICAL CO LTD (JP) 2018-05-30 EP disclosed
US-9422240-B2 Partially saturated nitrogen-containing heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2016-08-23 US disclosed
EP-2687507-B1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND TAISHO PHARMACEUTICAL CO LTD (JP) 2016-03-09 EP disclosed
US-20150175541-A1 PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND TAISHO PHARMACEUTICAL CO., LTD (JP) 2015-06-25 US disclosed
EP-2881384-A1 PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND Taisho Pharmaceutical Co., Ltd. (JP) 2015-06-10 EP disclosed
US-9035059-B2 Nitrogen-containing condensed heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-05-19 US disclosed
EP-2687507-A1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND Taisho Pharmaceutical Co., Ltd. (JP) 2014-01-22 EP disclosed
US-5360577-A MIXTURE OF OPTICALLY ACTIVE OXAZOLINE COMPOUND AND A LIQUID CRYSTALLINE CARRIER HOFFMANN-LA ROCHE INC. (US) 1994-11-01 US disclosed
US-5346647-A Cyclohexane compounds used in liquid crystalline mixtures HOFFMANN-LA ROCHE INC. (US) 1994-09-13 US disclosed
US-5288428-A Liquid crystal compounds having a terminal alkoxy propenyl group HOFFMANN-LA ROCHE INC. (US) 1994-02-22 US disclosed
EP-0559860-A1 HALOVINYL-DERIVATIVES. HOFFMANN LA ROCHE (CH) 1993-09-15 EP disclosed
EP-0559859-A1 FLUOROBENZONITRILES AND LIQUID CRYSTALLINE MIXTURES CONTAINING THEM MERCK PATENT GmbH (DE) 1993-09-15 EP disclosed
US-5238600-A IBIMETHYLENOXY CONTAINING LIQUID CRYSTAL COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 1993-08-24 US disclosed
US-5204018-A LIQUID CRYSTALS HOFFMANN-LA ROCHE INC. (US) 1993-04-20 US disclosed
WO-1993007234-A1 HALOVINYL-DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1993-04-15 WO disclosed
WO-1993007136-A1 FLUOROBENZONITRILES AND LIQUID CRYSTALLINE MIXTURES CONTAINING THEM F. HOFFMANN-LA ROCHE AG (CH) 1993-04-15 WO disclosed
US-5032312-A Liquid crystals HOFFMANN-LA ROCHE INC. (US) 1991-07-16 US disclosed