Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 11/20 | 0.77 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242160 | 0.99 | SERPINE1 (0.76) | SERPINE1NR1H4PTGER4PTGESALOX5 | |
| SCHEMBL1242182 | 0.90 | SERPINE1 (0.76) | SERPINE1NR1H4PTGER4 | |
| SCHEMBL1242152 | 0.89 | SERPINE1 (0.62) | SERPINE1NR1H4PTGER4PTGESALOX5 | |
| SCHEMBL1242162 | 0.89 | SERPINE1 (0.62) | SERPINE1NR1H4PTGER4PTGESALOX5 | |
| SCHEMBL1241464 | 0.89 | SERPINE1 (0.74) | SERPINE1NR1H4PTGER4 | |
| SCHEMBL1239623 | 0.87 | SERPINE1 (1.00) | SERPINE1NR1H4PTGESALOX5 | |
| SCHEMBL1241371 | 0.86 | SERPINE1 (0.80) | SERPINE1NR1H4 | |
| SCHEMBL1239730 | 0.85 | SERPINE1 (0.90) | SERPINE1NR1H4PTGESALOX5 | |
| SCHEMBL1241400 | 0.84 | SERPINE1 (0.93) | SERPINE1NR1H4PTGESALOX5 | |
| SCHEMBL1242512 | 0.84 | SERPINE1 (0.93) | SERPINE1NR1H4PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072498-A1 | N-PHENYLOXAMIDIC ACID DERIVATIVE | Institute of Medicinal Molecular Design, Inc. (JP) | 2009-06-24 | — | — | EP | disclosed |