SCHEMBL4004978

SCHEMBL4004978

CCCCCCCCCCCCCCCCC1(CCCCCCCCCCCCCCCC)CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
SIRT2 Q8IXJ6 1/20 0.36
CETP P11597 3/20 0.36
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
DNM1 Q05193 2/20 0.33
PTPN1 P18031 1/20 0.33
ACP1 P24666 1/20 0.33
CDC25B P30305 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959364 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1
SCHEMBL25392860 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1
SCHEMBL25392990 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1
SCHEMBL1345537 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1
SCHEMBL25392805 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1
SCHEMBL25390831 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1
SCHEMBL25391937 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1
SCHEMBL25390698 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1
SCHEMBL25391257 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1
SCHEMBL25392317 1.00 TSHR (0.40) TSHRTHRBSIRT2CETPCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7544352-B2 Cosmetic powder composition with improved moisturization properties and process for making and using same AVON PRODUCTS, INC (US) 2009-06-09 US disclosed
US-20060093565-A1 Pressed cosmetic powder and process for making AVON PRODUCTS, INC. 2006-05-04 US disclosed
EP-1583508-A4 COSMETIC POWDER COMPOSITION WITH IMPROVED MOISTURIZATION PROPERTIES AND PROCESS FOR MAKING AND USING SAME AVON PROD INC (US) 2006-01-11 EP disclosed
EP-1583508-A1 COSMETIC POWDER COMPOSITION WITH IMPROVED MOISTURIZATION PROPERTIES AND PROCESS FOR MAKING AND USING SAME AVON PRODUCTS, INC. (US) 2005-10-12 EP disclosed
WO-2004056327-A1 COSMETIC POWDER COMPOSITION WITH IMPROVED MOISTURIZATION PROPERTIES AND PROCESS FOR MAKING AND USING SAME AVON PRODUCTS, INC. (US) 2004-07-08 WO disclosed
US-20040120913-A1 Cosmetic powder composition with improved moisturization properties and process for making and using same AVON PRODUCTS, INC. 2004-06-24 US disclosed
US-20030133895-A1 Compressed, dry powder of a polysiloxane with superior binding properties, improved aesthetics, and a degree of springiness (elasticity) for ease of handling; JISA hardness index <45; pressing liquid binder and polymer at 800-2500 psi AVON PRODUCTS, INC. 2003-07-17 US disclosed