Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769399 | 0.92 | CALCRL (0.54) | CALCRL | |
| SCHEMBL4012298 | 0.91 | CALCRL (0.52) | CALCRL | |
| SCHEMBL4003427 | 0.91 | CALCRL (0.57) | CALCRL | |
| SCHEMBL4006748 | 0.89 | CALCRL (0.56) | CALCRL | |
| SCHEMBL4008402 | 0.89 | CALCRL (0.56) | CALCRL | |
| SCHEMBL13770204 | 0.89 | CALCRL (0.52) | CALCRL | |
| SCHEMBL4013464 | 0.89 | CALCRL (0.51) | CALCRL | |
| SCHEMBL13769787 | 0.89 | CALCRL (0.51) | CALCRL | |
| SCHEMBL4009533 | 0.88 | CALCRL (0.51) | CALCRL | |
| SCHEMBL13769702 | 0.88 | CALCRL (0.55) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080682-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080682-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |