Biphenyl

Biphenyl

SCHEMBL4006980

c1ccc(-c2ccc(-c3cccc4ccccc34)cc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.61
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA9 Q16790 3/20 0.61
TNF P01375 1/20 0.57
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.52
HPGD P15428 2/20 0.52
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
NFKB1 P19838 1/20 0.52
MAPK1 P28482 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
ATM Q13315 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HSD17B10 Q99714 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4894003 1.00 CA12 (0.61) CA12CA1CA2CA9TNF
SCHEMBL30258083 1.00 CA12 (0.61) CA12CA1CA2CA9TNF
Fluoride SCHEMBL28274296 0.98 CA12 (0.59) CA12CA1CA2CA9TNF
SCHEMBL29399206 0.95 TNF (0.61) CA12CA1CA2CA9TNF
SCHEMBL30122908 0.95 CA12 (0.66) CA12CA1CA2CA9TNF
SCHEMBL69345 0.95 TNF (0.61) CA12CA1CA2CA9TNF
SCHEMBL27988223 0.95 TNF (0.61) CA12CA1CA2CA9TNF
Hydrogen Sulfide SCHEMBL29156136 0.93 TNF (0.59) CA12CA1CA2CA9TNF
Methane SCHEMBL29181734 0.93 TNF (0.59) CA12CA1CA2CA9TNF
SCHEMBL27937443 0.93 TNF (0.59) CA12CA1CA2CA9TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009082157-A2 ARYL AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME DOOSAN CORPORATION (KR) 2009-07-02 WO disclosed