Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 11/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 11/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 11/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000431 | 0.83 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1ALOX5PTGS1 | |
| SCHEMBL4145032 | 0.83 | CYP2C8 (0.51) | CYP2C8MEN1MAPTKMT2AKDM4E | |
| SCHEMBL3003741 | 0.78 | CSNK2A2 (0.47) | CSNK2A2CSNK2BCSNK2A1ALOX5PTGS1 | |
| SCHEMBL12543138 | 0.77 | CSNK2A2 (0.51) | CSNK2A2CSNK2BCSNK2A1ALOX5ESR2 | |
| SCHEMBL3010649 | 0.77 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1ALOX5PTGS1 | |
| SCHEMBL3008056 | 0.77 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1ALOX5ESR2 | |
| SCHEMBL3997158 | 0.76 | CSNK2A2 (0.49) | CSNK2A2CSNK2BCSNK2A1ALOX5PTGS1 | |
| SCHEMBL3002388 | 0.76 | CSNK2A2 (0.49) | CSNK2A2CSNK2BCSNK2A1ALOX5ESR2 | |
| SCHEMBL4000434 | 0.75 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1ALOX5PTGS1 | |
| SCHEMBL3007045 | 0.72 | GAA (0.61) | CSNK2A2CSNK2BCSNK2A1ALOX5ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | claimed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | claimed |