Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.45 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.45 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008251 | 1.00 | IP6K1 (0.45) | IP6K1IP6K3IP6K2MAPTKMT2A | |
| SCHEMBL1242487 | 0.85 | KMT2A (0.42) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL1242745 | 0.83 | ERN1 (0.46) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL1242488 | 0.80 | AKR1C3 (0.43) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL12952842 | 0.79 | KMT2A (0.50) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL27928952 | 0.78 | MAPT (0.46) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL1148913 | 0.75 | AKR1C3 (0.51) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL13808882 | 0.75 | MEN1 (0.49) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL4446368 | 0.75 | FFAR4 (0.52) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL1238752 | 0.74 | FFAR4 (0.47) | MAPTKMT2AMEN1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072498-A1 | N-PHENYLOXAMIDIC ACID DERIVATIVE | Institute of Medicinal Molecular Design, Inc. (JP) | 2009-06-24 | — | — | EP | disclosed |