Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | NAA50 | Q9GZZ1 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621119 | 1.00 | CNR2 (0.49) | CNR2MAPK14MAPTLMNAMAPK11 | |
| SCHEMBL4010142 | 1.00 | CNR2 (0.49) | CNR2MAPK14MAPTLMNAMAPK11 | |
| SCHEMBL1621107 | 1.00 | CNR2 (0.49) | CNR2MAPK14MAPTLMNAMAPK11 | |
| SCHEMBL1621111 | 1.00 | CNR2 (0.49) | CNR2MAPK14MAPTLMNAMAPK11 | |
| SCHEMBL4172770 | 0.84 | CNR2 (0.46) | CNR2MAPK14 | |
| SCHEMBL4172767 | 0.84 | CNR2 (0.46) | CNR2MAPK14 | |
| SCHEMBL1620468 | 0.81 | CNR2 (0.55) | CNR2MAPK14MAPTLMNAMAPK11 | |
| SCHEMBL1621201 | 0.81 | CNR2 (0.41) | CNR2MAPK14MAPTLMNAMAPK11 | |
| SCHEMBL1621251 | 0.81 | CNR2 (0.41) | CNR2MAPK14MAPTLMNAMAPK11 | |
| SCHEMBL1621203 | 0.81 | CNR2 (0.41) | CNR2MAPK14MAPTLMNAMAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |