Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068825 | 0.89 | BTK (0.69) | BTK | |
| SCHEMBL13330128 | 0.89 | BTK (0.77) | BTK | |
| SCHEMBL1069098 | 0.88 | BTK (0.72) | BTK | |
| SCHEMBL1066339 | 0.88 | BTK (0.76) | BTK | |
| SCHEMBL1070603 | 0.88 | BTK (0.76) | BTK | |
| SCHEMBL1068822 | 0.88 | BTK (0.76) | BTK | |
| SCHEMBL1068492 | 0.88 | BTK (0.76) | BTK | |
| SCHEMBL1883374 | 0.87 | BTK (0.73) | BTK | |
| SCHEMBL1069061 | 0.87 | BTK (0.75) | BTK | |
| SCHEMBL1067971 | 0.87 | BTK (0.75) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068849-A2 | KINASE INHIBITORS, AND METHODS OF USING AND IDENTIFYING KINASE INHIBITORS | CGI Pharmaceuticals, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008033858-A2 | KINASE INHIBITORS, AND METHODS OF USING AND IDENTIFYING KINASE INHIBITORS | CGI PHARMACEUTICALS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |