Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | SLC33A1 | O00400 | 10/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302458 | 0.89 | LTB4R2 (0.49) | AGTR1SLC33A1LTB4R2PPARG | |
| SCHEMBL4011452 | 0.86 | SLC33A1 (0.52) | AGTR1SLC33A1LTB4R2PPARG | |
| SCHEMBL4016596 | 0.85 | SLC33A1 (0.50) | AGTR1SLC33A1LTB4R2PPARG | |
| SCHEMBL4011114 | 0.85 | PPARG (0.48) | SLC33A1PPARG | |
| SCHEMBL4305731 | 0.84 | PPARG (0.49) | AGTR1PPARG | |
| SCHEMBL4012948 | 0.84 | SLC33A1 (0.51) | SLC33A1PPARG | |
| SCHEMBL4011392 | 0.84 | PPARG (0.49) | AGTR1SLC33A1PPARG | |
| SCHEMBL4312422 | 0.82 | PPARG (0.44) | AGTR1SLC33A1LTB4R2PPARG | |
| SCHEMBL4009433 | 0.82 | PPARG (0.47) | AGTR1SLC33A1LTB4R2PPARG | |
| SCHEMBL4011145 | 0.78 | SLC33A1 (0.46) | SLC33A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |