⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4530797 | 1.00 | — | — | |
| SCHEMBL399963 | 1.00 | — | — | |
| SCHEMBL399964 | 1.00 | — | — | |
| SCHEMBL13654205 | 1.00 | — | — | |
| SCHEMBL404694 | 1.00 | — | — | |
| SCHEMBL13245423 | 0.96 | — | — | |
| SCHEMBL440343 | 0.96 | — | — | |
| SCHEMBL440342 | 0.96 | — | — | |
| SCHEMBL13654225 | 0.96 | — | — | |
| SCHEMBL1105536 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120154619-A | Application of CHIR-090 in preparation of pharmaceutical composition or vaccine for treating and/or preventing vibrio parahaemolyticus infection | 扬州大学 | 2025-06-17 | — | — | CN | claimed |
| US-20240175068-A1 | PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND/OR TREATMENT OF INFECTIONS AND ANTIBACTERIAL-INDUCED DYSFUNCTIONS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2024-05-30 | — | — | US | claimed |
| US-20120283175-A1 | ANTIBACTERIAL COMPOSITIONS | ACHAOGEN, INC. (US) | 2012-11-08 | — | — | US | claimed |
| WO-2011005355-A1 | COMBINATIONS COMPRISING A LPXC INHIBITOR AND AN ANTIBIOTIC FOR USE IN THE TREATMENT OF INFECTIONS CAUSED BY GRAM-NEGATIVE BACTERIA | ACHAOGEN, INC. (US) | 2011-01-13 | — | — | WO | claimed |
| US-20250346633-A1 | MACOLACINS AND METHODS OF USE THEREOF | UNIV ROCKEFELLER (US) | 2025-11-13 | — | — | US | disclosed |
| CN-120154619-A | Application of CHIR-090 in preparation of pharmaceutical composition or vaccine for treating and/or preventing vibrio parahaemolyticus infection | 扬州大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-120154619-A | Application of CHIR-090 in preparation of pharmaceutical composition or vaccine for treating and/or preventing vibrio parahaemolyticus infection | 扬州大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-120154619-A | Application of CHIR-090 in preparation of pharmaceutical composition or vaccine for treating and/or preventing vibrio parahaemolyticus infection | 扬州大学 | 2025-06-17 | — | — | CN | disclosed |
| US-20250171400-A1 | AZA-HETEROCYCLYL CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | X-BIOTIX THERAPEUTICS, INC. | 2025-05-29 | — | — | US | disclosed |
| US-20250099433-A1 | COMPOSITION AND METHOD FOR TREATMENT OF GRAM NEGATIVE BACTERIAL INFECTION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-03-27 | — | — | US | disclosed |
| US-12227475-B2 | Aza-heterocyclyl carboxamide and related compounds and their use in treating medical conditions | X-BIOTIX THERAPEUTICS, INC. | 2025-02-18 | — | — | US | disclosed |
| CN-119350185-A | Biphenyl hydroxamic derivative and preparation method and application thereof | 聊城大学 | 2025-01-24 | — | — | CN | disclosed |
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2008-10-30 | — | — | US | disclosed |
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
| US-20060154988-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2006-07-13 | — | — | US | disclosed |
| US-20040229955-A1 | intracellular inhibition of bacterial polypeptide deformylase in gramnegative bacteria, | UNIVERSITY OF WASHINGTON | 2004-11-18 | — | — | US | disclosed |