Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14114421 | 1.00 | USP2 (0.51) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL19410300 | 0.98 | HPGD (0.50) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL22931754 | 0.98 | HPGD (0.50) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL7620463 | 0.97 | MEN1 (0.50) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| Azetidine SCHEMBL5873670 | 0.96 | USP2 (0.55) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL6350119 | 0.96 | USP2 (0.55) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| Urea SCHEMBL2677784 | 0.95 | HPGD (0.48) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL10253840 | 0.95 | HPGD (0.54) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL14653322 | 0.95 | USP2 (0.53) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL1225127 | 0.93 | USP2 (0.58) | USP2SMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2551 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707806-A | Method for preparing chiral 2-aza-arene amide through visible light catalytic asymmetric reaction | 河南师范大学 | 2025-03-28 | — | — | CN | claimed |
| CN-118406439-B | Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing | 万华化学集团电子材料有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-118406439-A | Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing | 万华化学集团电子材料有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-118146226-A | Pyrrolo [2,3-d ] pyrimidine compound with nitrogen-containing heterocyclic structure, and preparation method and application thereof | 贵州大学 | 2024-06-07 | — | — | CN | claimed |
| CN-116947767-A | Human norepinephrine transporter body weight uptake inhibitor and preparation method and application thereof | 黄淮学院 | 2023-10-27 | — | — | CN | claimed |
| CN-115093794-B | Polysilicon polishing composition and application thereof | 万华化学集团电子材料有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116589405-A | Isoquinoline alkaloid derivative capable of efficiently inhibiting autophagy and reversing tumor multidrug resistance as well as preparation method and application thereof | 中国人民解放军陆军军医大学 | 2023-08-15 | — | — | CN | claimed |
| CN-115160310-B | Alternanthene derivatives as CDK2/Topo I inhibitors, preparation method thereof and antitumor application thereof | 中国人民解放军北部战区总医院 | 2023-06-23 | — | — | CN | claimed |
| CN-115650935-A | High-purity preparation method of homopiperazine derivative | 山东新华制药股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115160310-A | Sinomenine derivatives as CDK2/Topo I inhibitor, and preparation method and anti-tumor application thereof | 中国人民解放军北部战区总医院 | 2022-10-11 | — | — | CN | claimed |
| CN-115093794-A | Polysilicon polishing composition and application thereof | 万华化学集团电子材料有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-101495456-B | Substituted pyridyl amide compounds as modulators of the histamine H3 receptor | JANSSEN PHARMACEUTICA NV | 2014-03-19 | — | — | CN | claimed |
| CN-103360330-A | Synthetic method for homopiperazine | LIU HUAIZHEN | 2013-10-23 | — | — | CN | claimed |
| US-20260146042-A1 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2026-05-28 | — | — | US | disclosed |
| EP-4027995-B1 | HPK1 ANTAGONISTS AND USES THEREOF | NIMBUS SATURN INC (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-4747243-A1 | LIGANDS AND COMPOSITIONS AND METHODS OF USE THEREOF | Baylor College of Medicine (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-0574906-A2 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |