Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.82 |
| ▸ | TACR2 | P21452 | 1/20 | 0.80 |
| ▸ | CNR2 | P34972 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704550 | 1.00 | CNR1 (0.82) | CNR1TACR2CNR2 | |
| SCHEMBL1378063 | 0.93 | CNR1 (0.82) | CNR1TACR2CNR2 | |
| SCHEMBL1378062 | 0.93 | CNR1 (0.82) | CNR1TACR2CNR2 | |
| SCHEMBL2705566 | 0.91 | CNR1 (0.84) | CNR1TACR2CNR2 | |
| SCHEMBL2704102 | 0.90 | CNR1 (1.00) | CNR1TACR2CNR2 | |
| SCHEMBL1377904 | 0.90 | CNR1 (0.91) | CNR1TACR2CNR2 | |
| SCHEMBL1377255 | 0.89 | CNR1 (1.00) | CNR1TACR2CNR2 | |
| SCHEMBL5271693 | 0.89 | CNR1 (1.00) | CNR1TACR2CNR2 | |
| SCHEMBL1377250 | 0.89 | CNR1 (1.00) | CNR1TACR2CNR2 | |
| SCHEMBL1376708 | 0.89 | CNR1 (1.00) | CNR1TACR2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074096-A1 | 3-PYRIDINECARBOXAMIDE AND 2-PYRAZINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008040651-A1 | 3-PYRIDINECARBOXAMIDE AND 2-PYRAZINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-10 | — | — | WO | disclosed |