SCHEMBL4010966

SCHEMBL4010966

Cn1cc(-c2cccc(NC(=O)c3ccc(C(C)(C)C)cc3)c2F)nc(Nc2ccc(N3CC[SH2]CC3=O)cc2)c1=O

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BTK Q06187 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1069407 0.85 BTK (0.71) BTK
SCHEMBL4005295 0.84 BTK (0.61) BTK
SCHEMBL4001942 0.84 BTK (0.55) BTK
SCHEMBL1068536 0.84 BTK (0.62) BTK
SCHEMBL4008738 0.84 BTK (0.70) BTK
SCHEMBL1068288 0.83 BTK (0.63) BTK
SCHEMBL3998450 0.83 BTK (0.64) BTK
SCHEMBL1069505 0.83 BTK (0.61) BTK
SCHEMBL1068576 0.83 BTK (0.57) BTK
SCHEMBL1067788 0.82 BTK (0.72) BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2068849-A2 KINASE INHIBITORS, AND METHODS OF USING AND IDENTIFYING KINASE INHIBITORS CGI Pharmaceuticals, Inc. (US) 2009-06-17 EP disclosed
WO-2008033858-A2 KINASE INHIBITORS, AND METHODS OF USING AND IDENTIFYING KINASE INHIBITORS CGI PHARMACEUTICALS, INC. (US) 2008-03-20 WO disclosed