Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 17/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011044 | 1.00 | CHRM3 (0.53) | CHRM3ADRB2 | |
| SCHEMBL14199543 | 0.90 | CHRM3 (0.61) | CHRM3ADRB2 | |
| SCHEMBL14199532 | 0.88 | CHRM3 (0.68) | CHRM3ADRB2 | |
| SCHEMBL14199536 | 0.87 | CHRM3 (0.61) | CHRM3ADRB2 | |
| SCHEMBL4995653 | 0.86 | CHRM3 (0.41) | CHRM3ADRB2 | |
| SCHEMBL4995661 | 0.86 | CHRM3 (0.41) | CHRM3ADRB2 | |
| SCHEMBL1256428 | 0.86 | CHRM3 (0.62) | CHRM3ADRB2 | |
| SCHEMBL1256430 | 0.86 | CHRM3 (0.62) | CHRM3ADRB2 | |
| SCHEMBL2841337 | 0.86 | CHRM3 (0.62) | CHRM3ADRB2 | |
| SCHEMBL4018273 | 0.84 | CHRM3 (0.40) | CHRM3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074094-A1 | SULFONAMIDE DERIVATIVES AS ADRENERGIC AGONISTS AND MUSCARINIC ANTAGONISTS | Pfizer Limited (GB) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008041095-A1 | SULFONAMIDE DERIVATIVES AS ADRENERGIC AGONISTS AND MUSCARINIC ANTAGONISTS | PFIZER LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |