Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 18/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011086 | 0.81 | P2RY12 (0.53) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4011089 | 0.79 | P2RY12 (0.69) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL3591310 | 0.79 | P2RY12 (0.72) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL5054376 | 0.78 | P2RY12 (0.46) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL3589555 | 0.74 | P2RY12 (0.71) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL3582742 | 0.72 | P2RY12 (0.71) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4737030 | 0.72 | P2RY12 (0.86) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4739509 | 0.71 | P2RY12 (0.74) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL3588257 | 0.71 | P2RY12 (0.83) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL3586610 | 0.70 | P2RY12 (0.73) | P2RY12CYP2C9CYP3A4CHRM2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044050-A1 | NEW PYRIDINE ANALOGUES | Astra Zeneca AB (SE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008004946-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |