Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.74 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.56 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558477 | 0.86 | CETP (0.81) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL3722694 | 0.84 | CETP (0.88) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL4182800 | 0.84 | CETP (1.00) | CETP | |
| SCHEMBL3556670 | 0.81 | CETP (0.90) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL17993997 | 0.81 | CETP (0.74) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL9885342 | 0.81 | CETP (0.74) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL3726400 | 0.80 | CETP (0.81) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL3554307 | 0.80 | CETP (0.88) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL3553312 | 0.80 | CETP (0.88) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL3554912 | 0.80 | CETP (0.88) | CETPTBXA2RPTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737811-A4 | CETP INHIBITORS | MERCK & CO INC (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1737811-A1 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100298-A1 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2005-10-27 | — | — | WO | disclosed |