⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22322507 | 0.78 | — | — | |
| SCHEMBL6626520 | 0.75 | CYP3A4 (0.42) | — | |
| SCHEMBL5777397 | 0.75 | — | — | |
| SCHEMBL11426008 | 0.72 | TSHR (0.62) | — | |
| Triethyl Phosphate SCHEMBL21887 | 0.72 | TSHR (1.00) | — | |
| Triethyl Phosphate SCHEMBL27822049 | 0.72 | TSHR (1.00) | — | |
| Triethyl Phosphate SCHEMBL28023664 | 0.72 | TSHR (1.00) | — | |
| Triethyl Phosphate SCHEMBL1332591 | 0.72 | TSHR (1.00) | — | |
| SCHEMBL5771057 | 0.71 | CYP3A4 (0.64) | — | |
| SCHEMBL10988680 | 0.71 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3706899-A1 | BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS | The Government Of The United States Of America As The Secretary of The Navy (US) | 2020-09-16 | — | — | EP | claimed |
| US-20190134601-A1 | BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2019-05-09 | — | — | US | claimed |
| EP-1415537-B1 | Combinations of herbicides and safeners | BAYER CROPSCIENCE AG (DE) | 2009-11-11 | — | — | EP | claimed |
| US-7572914-B2 | Kinase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-08-11 | — | — | US | claimed |
| US-20080153869-A1 | Kinase Inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-06-26 | — | — | US | claimed |
| EP-1773807-A2 | KINASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-04-18 | — | — | EP | claimed |
| US-7129253-B2 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-31 | — | — | US | claimed |
| EP-1694686-A1 | KINASE INHIBITORS | Takeda San Diego, Inc. (US) | 2006-08-30 | — | — | EP | claimed |
| WO-2005123672-A2 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-12-29 | — | — | WO | claimed |
| US-20050153966-A1 | Kinase inhibitors | SYRRX, INC. | 2005-07-14 | — | — | US | claimed |
| US-20030069430-A1 | Substituted oxindole derivatives as protein tyrosine and as protein serine/threonine kinase inhibitors and compositions and methods of treating chemotherapy and radiation therapy side effects | SMITHKLINE BEECHAM CORPORATION | 2003-04-10 | — | — | US | claimed |
| US-6498176-B1 | INHIBITING TUMOR GROWTH VIA INHIBITION OF TUMOR-RELATED ANGIOGENESIS | SMITHKLINEBEECHAM CORPORATION | 2002-12-24 | — | — | US | claimed |
| US-20020099071-A1 | Protein tyrosine kinase and protein serin/threonine kinase inhibitory activity; anticancer agents; treating chemotherapy induced alopecia | GLENNON KIMBERLEY CAROLINE (US) | 2002-07-25 | — | — | US | claimed |
| US-6350747-B1 | PROTEIN SERINE/THREONINE KINASE AND PROTEIN TYROSINE KINASE ENZYME INHIBITORS; ANGIOGENESIS INHIBITORS; ANTITUMOR AND ANTIPROLIFERATIVE AGENTS | GLAXO WELLCOME INC. | 2002-02-26 | — | — | US | claimed |
| EP-1165514-A1 | 3-(ANILINOMETHYLENE) OXINDOLES AS PROTEIN TYROSINE KINASE AND PROTEIN SERINE/THREONINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2002-01-02 | — | — | EP | claimed |
| WO-2000056710-A1 | 3-(ANILINOMETHYLENE) OXINDOLES AS PROTEIN TYROSINE KINASE AND PROTEIN SERINE/THREONINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-09-28 | — | — | WO | claimed |
| EP-0404190-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-10-25 | — | — | EP | claimed |
| US-5304549-A | Control or prevention of degenerative joint diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-04-19 | — | — | US | claimed |
| EP-0244835-B1 | LANGMUIR-BLODGETT ULTRATHIN MEMBRANE OF POLYFUMURATE | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1992-08-26 | — | — | EP | claimed |
| EP-0098159-B1 | PREPARATION OF N-PHOSPHONOMETHYLGLYCINE | STAUFFER CHEMICAL COMPANY (US) | 1986-09-03 | — | — | EP | claimed |