Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.61 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040860 | 0.93 | TAAR1 (0.59) | TAAR1IDO1GPR52TSHRCYP2A13 | |
| SCHEMBL1458748 | 0.82 | TAAR1 (0.75) | TAAR1IDO1GPR52TSHR | |
| SCHEMBL8589724 | 0.82 | TAAR1 (0.52) | TAAR1IDO1GPR52TSHRHSD17B10 | |
| SCHEMBL29351396 | 0.80 | TAAR1 (0.71) | TAAR1IDO1GPR52TSHRCYP2A13 | |
| SCHEMBL6738136 | 0.80 | TAAR1 (0.71) | TAAR1IDO1GPR52TSHRCYP2A13 | |
| SCHEMBL29653394 | 0.79 | TAAR1 (0.58) | TAAR1IDO1GPR52TSHRCYP2A13 | |
| SCHEMBL216838 | 0.79 | TAAR1 (0.58) | TAAR1IDO1GPR52TSHRCYP2A13 | |
| SCHEMBL23043471 | 0.78 | TAAR1 (0.38) | TAAR1TSHRCYP1A2HSD17B10 | |
| SCHEMBL2047663 | 0.77 | TAAR1 (0.56) | TAAR1IDO1GPR52TSHRCYP2A13 | |
| SCHEMBL8071390 | 0.77 | TAAR1 (0.56) | TAAR1IDO1GPR52TSHRCYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104602524-A | Pesticidal compositions and methods related thereto | DOW AGROSCIENCES LLC | 2015-05-06 | — | — | CN | disclosed |
| CN-103826452-A | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC | 2014-05-28 | — | — | CN | disclosed |
| US-7514127-B2 | Dibenzofuran derivatives, dibenzothiophene derivatives and fluorene derivatives | MERCK PATENT GMBH (DE) | 2009-04-07 | — | — | US | disclosed |
| US-20070219380-A1 | Dibenzofuran Derivatives, Dibenzothiophene Derivatives and Fluorene Derivatives | MERCK PATENT GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219380-A1 | Dibenzofuran Derivatives, Dibenzothiophene Derivatives and Fluorene Derivatives | ZYX, F3, YBX1 | TAAR1 993/4885IDO1 551/4885GPR52 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.