Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.35 |
| ▸ | SERPINA3 | P01011 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011846 | 0.96 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1ERBB2SERPINA3 | |
| SCHEMBL4017351 | 0.95 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL4016224 | 0.92 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL4011271 | 0.91 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL4017430 | 0.90 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL4980227 | 0.90 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL4981469 | 0.90 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL4013222 | 0.90 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL4010194 | 0.90 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL4011139 | 0.89 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074126-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | disclosed |
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
| WO-2008049105-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | HSP90AB2P, HSP90AB1, HSP90AA1 | HSP90AA1 3/4885HSP90AB1 2/4885ERBB2 1826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.