SCHEMBL4012010

SCHEMBL4012010

CCCCCCCC/C=C\CCCCCCCC(O)C=CCCCCCCCCC

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.59
GPR132 Q9UNW8 1/20 0.59
MEN1 O00255 1/20 0.55
CYP3A4 P08684 1/20 0.55
KMT2A Q03164 1/20 0.55
MAPT P10636 2/20 0.53
TRPA1 O75762 1/20 0.53
DDAH1 O94760 1/20 0.53
GAPDH P04406 1/20 0.53
SPHK2 Q9NRA0 2/20 0.53
SPHK1 Q9NYA1 2/20 0.53
CETP P11597 1/20 0.53
FFAR1 O14842 1/20 0.53
FFAR4 Q5NUL3 1/20 0.53
LTB4R2 Q9NPC1 1/20 0.53
ALOX5 P09917 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26968802 1.00 PPARG (0.59) PPARGGPR132MEN1CYP3A4KMT2A
SCHEMBL9648008 0.98 PPARG (0.61) PPARGGPR132MEN1CYP3A4KMT2A
SCHEMBL812290 0.98 PPARG (0.61) PPARGGPR132MEN1CYP3A4KMT2A
SCHEMBL11853316 0.98 PPARG (0.61) PPARGGPR132MEN1CYP3A4KMT2A
SCHEMBL9648002 0.98 PPARG (0.61) PPARGGPR132MEN1CYP3A4KMT2A
SCHEMBL11855470 0.98 PPARG (0.61) PPARGGPR132MEN1CYP3A4KMT2A
SCHEMBL812291 0.98 PPARG (0.61) PPARGGPR132MEN1CYP3A4KMT2A
SCHEMBL2264995 0.98 PPARG (0.61) PPARGGPR132MEN1CYP3A4KMT2A
SCHEMBL11853321 0.98 PPARG (0.61) PPARGGPR132MEN1CYP3A4KMT2A
SCHEMBL11855461 0.98 PPARG (0.61) PPARGGPR132MEN1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1639988-B1 Cosmetic solid W/O emulsion OREAL (FR) 2009-06-17 EP disclosed
EP-1795233-A2 Cosmetic composition comprising an ester of dimerdilinoleic acid and polyol and a silicon containing surfactant L'OREAL (FR) 2007-06-13 EP disclosed
EP-1655013-A2 Cosmetic solid W/O emulsion L'OREAL (FR) 2006-05-10 EP disclosed
EP-1639988-A2 Cosmetic solid W/O emulsion L'OREAL (FR) 2006-03-29 EP disclosed
EP-1640040-A1 Cosmetic composition comprising a polymer of silicon L'OREAL (FR) 2006-03-29 EP disclosed
EP-1632269-A1 Cosmetic composition comprising a defined polymeric silicon and a surfactant L'OREAL (FR) 2006-03-08 EP disclosed
EP-1623700-A1 Cosmetic composition showing an improved hold L'OREAL (FR) 2006-02-08 EP disclosed
EP-1621230-A1 Cosmetic composition comprising a defined polymeric silicone and a gelling agent L'OREAL (FR) 2006-02-01 EP disclosed
EP-1616558-A1 Bilayered cosmetic product comprising a silicone polymer L'OREAL (FR) 2006-01-18 EP disclosed
EP-1616557-A2 Cosmetic composition containing a selected silicone polymer and a film-forming agent L'OREAL (FR) 2006-01-18 EP disclosed