Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.56 |
| ▸ | TACR2 | P21452 | 1/20 | 0.56 |
| ▸ | CTSA | P10619 | 6/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2702570 | 0.85 | CNR1 (0.58) | CNR1TACR2CTSAABL1CNR2 | |
| SCHEMBL3846700 | 0.80 | CNR1 (0.57) | CNR1TACR2CTSAABL1CNR2 | |
| SCHEMBL2703081 | 0.79 | CNR1 (0.65) | CNR1TACR2CTSAABL1CNR2 | |
| SCHEMBL1376961 | 0.79 | CNR1 (0.67) | CNR1TACR2CTSACNR2 | |
| SCHEMBL2702655 | 0.79 | CNR1 (0.59) | CNR1TACR2CTSAABL1CNR2 | |
| SCHEMBL1377692 | 0.79 | CNR1 (0.59) | CNR1TACR2CTSAABL1CNR2 | |
| SCHEMBL2703056 | 0.78 | CNR1 (0.63) | CNR1TACR2CTSAABL1CNR2 | |
| SCHEMBL3845638 | 0.78 | CNR1 (0.58) | CNR1TACR2CTSAABL1CNR2 | |
| SCHEMBL2704311 | 0.77 | CNR1 (0.56) | CNR1TACR2CTSAABL1CNR2 | |
| SCHEMBL1377601 | 0.76 | CNR1 (0.80) | CNR1TACR2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074096-A1 | 3-PYRIDINECARBOXAMIDE AND 2-PYRAZINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2009-07-01 | — | — | EP | claimed |
| WO-2008040651-A1 | 3-PYRIDINECARBOXAMIDE AND 2-PYRAZINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-10 | — | — | WO | claimed |
| EP-2074096-A1 | 3-PYRIDINECARBOXAMIDE AND 2-PYRAZINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008040651-A1 | 3-PYRIDINECARBOXAMIDE AND 2-PYRAZINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-10 | — | — | WO | disclosed |