Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621282 | 0.93 | CNR2 (0.64) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL4012799 | 0.87 | CNR2 (0.56) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL4011532 | 0.83 | CNR2 (0.52) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL766898 | 0.81 | CNR1 (0.56) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL4011530 | 0.79 | CNR2 (0.50) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL3655047 | 0.79 | CNR2 (0.60) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL1621234 | 0.78 | CNR2 (0.64) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL3653682 | 0.78 | CNR2 (0.58) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL1621505 | 0.77 | CNR1 (0.63) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL1620681 | 0.77 | CNR2 (0.57) | CNR2CNR1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |