Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 3/20 | 0.38 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.37 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621338 | 0.92 | NPY5R (0.51) | NPY5RGCKCNR1CNR2EPHX2 | |
| SCHEMBL1621229 | 0.91 | NPY5R (0.53) | NPY5RGCKCNR1CNR2EPHX2 | |
| SCHEMBL1618845 | 0.91 | NPY5R (0.53) | NPY5RGCKCNR1CNR2EPHX2 | |
| SCHEMBL1621445 | 0.91 | NPY5R (0.53) | NPY5RGCKCNR1CNR2EPHX2 | |
| SCHEMBL1620950 | 0.90 | NPY5R (0.54) | NPY5RGCKCNR1CNR2EPHX2 | |
| SCHEMBL4011949 | 0.90 | CNR2 (0.55) | NPY5RGCKCNR1CNR2 | |
| SCHEMBL1621285 | 0.89 | NPY5R (0.52) | NPY5RGCKCNR1CNR2EPHX2 | |
| SCHEMBL1619579 | 0.84 | NPY5R (0.49) | NPY5RGCKCNR1CNR2EPHX2 | |
| SCHEMBL1619860 | 0.84 | CNR2 (0.51) | NPY5RGCKCNR1CNR2EPHX2 | |
| SCHEMBL4013229 | 0.82 | CNR2 (0.56) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |