Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 18/20 | 0.54 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128559 | 0.90 | P2RY12 (0.42) | P2RY12USP28KDM1ACYP2C9 | |
| SCHEMBL5120517 | 0.88 | P2RY12 (0.41) | P2RY12USP28KDM1ACYP2C9 | |
| SCHEMBL5124872 | 0.88 | P2RY12 (0.43) | P2RY12USP28KDM1A | |
| SCHEMBL4011274 | 0.81 | P2RY12 (0.69) | P2RY12 | |
| SCHEMBL4228562 | 0.81 | P2RY12 (0.69) | P2RY12 | |
| SCHEMBL5115747 | 0.81 | P2RY12 (0.62) | P2RY12CYP2C9 | |
| SCHEMBL13764368 | 0.78 | P2RY12 (0.53) | P2RY12USP28 | |
| SCHEMBL4750389 | 0.76 | P2RY12 (0.73) | P2RY12 | |
| SCHEMBL4750386 | 0.76 | P2RY12 (0.73) | P2RY12 | |
| SCHEMBL13768967 | 0.73 | P2RY12 (0.57) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566722-B2 | Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-07-28 | — | — | US | disclosed |