Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.55 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153928 | 0.89 | AKR1C3 (0.52) | PTGER4DNMT3AAKR1C3MAPTLMNA | |
| SCHEMBL1154066 | 0.86 | AKR1C3 (0.55) | PTGER4DNMT3AAKR1C3MAPTLMNA | |
| SCHEMBL4014975 | 0.82 | PTGER4 (0.60) | PTGER4AKR1C3LMNANPC1RAB9A | |
| SCHEMBL1154387 | 0.82 | DNMT3A (0.55) | PTGER4DNMT3AAKR1C3NPC1RAB9A | |
| SCHEMBL691790 | 0.81 | PTGER4 (0.66) | PTGER4LMNAPTGER2 | |
| SCHEMBL15541938 | 0.81 | PTGER4 (0.81) | PTGER4DNMT3ALMNAHDAC1HDAC6 | |
| SCHEMBL4014415 | 0.81 | PTGER4 (0.64) | PTGER4AKR1C3MAPTLMNANPC1 | |
| SCHEMBL1153664 | 0.81 | PTGER4 (0.59) | PTGER4DNMT3AAKR1C3MAPTLMNA | |
| SCHEMBL1154190 | 0.81 | DNMT3A (0.52) | PTGER4DNMT3AAKR1C3MAPTLMNA | |
| SCHEMBL1154062 | 0.81 | CNR2 (0.50) | PTGER4DNMT3AHDAC1HDAC6NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756043-B1 | ORTHO SUBSTITUTED ARYL OR HETEROARYL AMIDE COMPOUNDS | RAQUALIA PHARMA INC (JP) | 2009-07-01 | — | — | EP | disclosed |