Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621075 | 0.94 | CNR2 (0.54) | CNR2CNR1MAPK14KDM1AMAPT | |
| SCHEMBL1620468 | 0.91 | CNR2 (0.55) | CNR2CNR1MAPK14KDM1AMAPT | |
| SCHEMBL1621077 | 0.91 | CNR2 (0.57) | CNR2MAPK14MAPTLMNAMAPK11 | |
| SCHEMBL4017781 | 0.91 | CNR2 (0.52) | CNR2CNR1 | |
| SCHEMBL1619502 | 0.90 | CNR2 (0.58) | CNR2MAPK14MAPTLMNAMAPK11 | |
| SCHEMBL766858 | 0.84 | CNR2 (0.57) | CNR2CNR1MAPK14KDM1AMAPT | |
| SCHEMBL4017454 | 0.82 | CNR2 (0.42) | CNR2CNR1MAPK14KDM1ANTRK1 | |
| SCHEMBL4011546 | 0.82 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL4013638 | 0.80 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL766896 | 0.80 | CNR2 (0.57) | CNR2CNR1MAPK14MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |