Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.58 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 10/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 10/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013425 | 0.90 | PDE10A (0.62) | PDE10APDK4GRM5GRM1HTR6 | |
| SCHEMBL4008377 | 0.89 | PDE10A (0.58) | PDE10APDK4GRM5GRM1HTR6 | |
| SCHEMBL4016330 | 0.88 | PDE10A (0.59) | PDE10APDK4GRM5GRM1HTR6 | |
| SCHEMBL13770040 | 0.88 | PDE10A (0.60) | PDE10APDK4GRM5GRM1HTR6 | |
| SCHEMBL29691225 | 0.87 | PDK4 (0.64) | PDE10APDK4GRM5GRM1HTR6 | |
| SCHEMBL13993115 | 0.87 | PDK4 (0.64) | PDE10APDK4GRM5GRM1HTR6 | |
| SCHEMBL13769826 | 0.85 | PDE10A (0.69) | PDE10APDK4GRM5GRM1HTR6 | |
| SCHEMBL13769848 | 0.85 | PDE10A (0.60) | PDE10APDK4GRM5GRM1HTR6 | |
| SCHEMBL4013686 | 0.85 | GRM1 (0.58) | PDE10APDK4GRM5GRM1HTR6 | |
| SCHEMBL4013818 | 0.84 | PDE10A (0.55) | PDE10APDK4GRM5GRM1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |