Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 18/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012480 | 0.91 | NR1H2 (0.58) | NR1H2NR1H3NR4A2 | |
| SCHEMBL4013824 | 0.89 | NR1H2 (0.56) | NR1H2NR1H3 | |
| SCHEMBL4013205 | 0.88 | NR1H2 (0.60) | NR1H2NR1H3 | |
| SCHEMBL4011423 | 0.88 | NR1H2 (0.52) | NR1H2NR1H3NR4A2 | |
| SCHEMBL4017985 | 0.86 | NR1H3 (0.57) | NR1H2NR1H3NR4A2 | |
| SCHEMBL4019268 | 0.83 | NR1H2 (0.59) | NR1H2NR1H3 | |
| SCHEMBL4012431 | 0.83 | NR1H2 (0.56) | NR1H2NR1H3NR4A2 | |
| SCHEMBL4013631 | 0.81 | NR1H2 (0.46) | NR1H2NR1H3NR4A2 | |
| SCHEMBL3507103 | 0.81 | NR1H2 (0.49) | NR1H2NR1H3 | |
| SCHEMBL4017788 | 0.80 | NR1H2 (0.59) | NR1H2NR1H3NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | claimed |
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |